Installation

METALoci has only been tested in Ubuntu and Manjaro Linux distributions. MacOS support is not guaranteed.

Install metaloci from PyPI:

conda create -n metaloci -c bioconda python==3.12 bedtools
conda activate metaloci
pip install metaloci

Do you have trouble compiling dependencies? Perhaps you need an upgraded version of libcurl.

In Ubuntu, you can install it with:

sudo apt install -y libcurl4-openssl-dev

If you are experiencing any unexpected results with METALoci (e.g. your signal after binning is 0 for every bin), we suggest to update the version of awk you are using. The recommended version is 5.1.0 or newer.

In Ubuntu, you can do this with:

sudo apt install gawk